Pharmagel^® Ag is hydrogel wound dressing sheet that combines antimicrobial effect of silver with fluid management, cooling sensation and moisturizing effect of hydrogel to provide ideal environment for wound healing.Pharmagel^® Ag est laminé avec une couche extérieure de film de polyuréthane résistant aux bactéries, aux virus et à l'eau.

Broad spectrum antimicrobial effect:

Thanks to the antimicrobial power of silver ions. Pharmagel^® Ag shows antimicrobial effect against a wide spectrum of microorganisms including Gram-negative bacteria such as Escherichia coli and pseudomonas aeruginosa; Gram-positive bacteria such as Staphylococcus aureus and MRSA; and VRE; and fungi such as Aspergillus niger and Penicillium nigricans.

Continuous antimicrobial protection:

Pharmagel^® Ag release of silver is highly controlled, these silver particles are found on the surface of the silica and also embedded throughout the structure.

The metallic silver particles act as a reservoir for release of silver ions (Ag+) that are the active agent against bacteria. The presence of both surface and embedded silver particles gives the material a combination of immediate antimicrobial activity combined with long-term durability.

In fact large amounts of silver are unnecessary and can actually be cytotoxic to fibroblasts; That is why the antimicrobial effect of Pharmagel^® Ag  long lasting.

Non-staining to skin:

Since silver is controllably released from the porous amorphous silicon dioxide structure, it does not stain skin. Other silver dressings, which lack control over release of silver, may cause staining of surrounding tissues or lead to cytotoxicity of tissue cells which are typically found in the wound bed.

These cells are necessary for wound healing processes such asproliferation, angiogenesis and matrix protein deposition.

Photostable:

Pharmagel^® Ag does not darken on exposure to light.

Pharmagel^® Ag:

For use on partial and full thickness wounds, including:

• Brûlures du premier et deuxième degré
• Recouvrement de greffons
• Sites chirurgicaux
• Ulcères diabétiques
• Ulcères veineux
• Escarres

Pharmagel^® Ag should not be used on third degree burns; also it should not be used neither on highly exuding wound nor exposed muscles, bones or tendons Sensitivity to any of the product’s ingredients.

L’utilisation est limitée pour les néonataux, les nourrissons et durant la grossesse.

1. Un dommage de la membrane des cellules bactériennes peut entraîner une fuite du cytoplasme des cellules pouvant causer une déshydratation et un rétrécissement des cellules.
2. Les atomes d’argent se lient aux groupes thiols (-SH) dans les enzymes, et par conséquent entraînent la désactivation des enzymes.
3. L’argent est associé à l’ADN une fois qu’il pénètre dans les cellules empêchant ainsi une réplication des cellules bactériennes.