Pharmagel^® Ag is hydrogel wound dressing sheet that combines antimicrobial effect of silver with fluid management, cooling sensation and moisturizing effect of hydrogel to provide ideal environment for wound healing.Pharmagel^® Ag jest laminowany odporną na bakterie, wirusy i wodoodporną zewnętrzną warstwą folii poliuretanowej.

Broad spectrum antimicrobial effect:

Thanks to the antimicrobial power of silver ions. Pharmagel^® Ag shows antimicrobial effect against a wide spectrum of microorganisms including Gram-negative bacteria such as Escherichia coli and pseudomonas aeruginosa; Gram-positive bacteria such as Staphylococcus aureus and MRSA; and VRE; and fungi such as Aspergillus niger and Penicillium nigricans.

Continuous antimicrobial protection:

Pharmagel^® Ag release of silver is highly controlled, these silver particles are found on the surface of the silica and also embedded throughout the structure.

The metallic silver particles act as a reservoir for release of silver ions (Ag+) that are the active agent against bacteria. The presence of both surface and embedded silver particles gives the material a combination of immediate antimicrobial activity combined with long-term durability.

In fact large amounts of silver are unnecessary and can actually be cytotoxic to fibroblasts; That is why the antimicrobial effect of Pharmagel^® Ag  long lasting.

Brak przebarwień skóry:

Since silver is controllably released from the porous amorphous silicon dioxide structure, it does not stain skin. Other silver dressings, which lack control over release of silver, may cause staining of surrounding tissues or lead to cytotoxicity of tissue cells which are typically found in the wound bed.

These cells are necessary for wound healing processes such asproliferation, angiogenesis and matrix protein deposition.

Fotostabilność:

Pharmagel^® Ag does not darken on exposure to light.

Pharmagel^® Ag:

For use on partial and full thickness wounds, including:

• oparzenia pierwszego i drugiego stopnia,
• Pokrycie przeszczepów
• Miejsca chirurgiczne
• Wrzody cukrzycowe
• Owrzodzenia żylne
• Odleżyny

Pharmagel^® Ag should not be used on third degree burns; also it should not be used neither on highly exuding wound nor exposed muscles, bones or tendons Sensitivity to any of the product’s ingredients.

Badania dotyczące bezpieczeństwa stosowania u noworodków, niemowląt i w czasie ciąży przeprowadzono w ograniczonym zakresie.

1. Niszczy błonę komórkową bakterii, powodując wyciekcytoplazmy z komórki i prowadząc do jej odwodnieniai obkurczenia.
2. Atomy srebra wiążą się z grupami tiolowymi (-SH) enzymów,co powoduje ich dezaktywację.
3. Srebro po przedostaniu się do komórki wiąże się z łańcuchem DNA,uniemożliwiając replikację komórek bakterii.